Paradoxical suboptimal vitamin D levels in a Mediterranean region: a population-based study


Catalonia has an adult population of > 6 million9 and 25(OH)D levels have only recently been studied in about half a million, implying detection of seven and state6 recommendations, which only recommend measures in the population at risk defined as hospitalized people, institutionalized elderly people, people in prolonged immobilization, those with neoplastic diseases, those with other skin diseases that should not be expose to the sun or those with gastrointestinal malabsorption and pregnant women.

Our results show that 25(OH)D measurements as well as vitamin D supplementation are not only focused on the population ≥ 45 years old, but also and especially on women, which does not correspond to the groups at risk of deficiency. described by the European European Society of Endocrinology, which also recommends more population measurements to know the status of vitamin D in Europe5.

While the young people measured had high deficiency rates, the prescription for vitamin D supplementation was very low. This is consistent with the conclusion, with evidence grade B, that treatment of asymptomatic people with identified impairment has not been shown to improve healthten. Nevertheless, there is an inverted J-shaped association between 25(OH)D and all-cause mortality.11 and there could be specific symptoms or non-skeletal disease states for which vitamin D measurement and supplementation improve health. Specifically, the need to create more defined randomized clinical trials, not only with larger populations12 but also with more specific and better analyzed designs, became evident13 as has already been shown for 25(OH)D and vitamin D supplementation14.


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